The AUC of ALB was 0.681, P < 0.05, and the best cut-off value was 44.2 g/L. An ROC curve was constructed using ALB and the total number of lesions.

Multivariate logistic regression analysis showed that ALB, total number of lesions, and drug use were independent influencing factors of the degree of disability in patients with MS, and the difference was statistically significant ( P < 0.05). Univariate analysis showed that age, annual recurrence rate (ARR), drug use, albumin (ALB), triglycerides (TG), and total number of lesions in groups with EDSS score ≤3 were significantly different from those with an EDSS score > 3 points ( P < 0.05). Results: Among 72 patients with RRMS, 45 (62.5%) had an EDSS score ≤3 A total of 27 patients (37.5%) had an EDSS score >3 points. All patients completed craniocerebral and spinal cord MRI (with or without Gd enhancement) and were evaluated for Expanded Disability Status Score (EDSS) scores before receiving treatment. Methods: This retrospective observational study included 72 patients with relapsing-remitting multiple sclerosis (RRMS) at the First Hospital of Shanxi Medical University. Objective: To explore the factors influencing the degree of disability in patients with multiple sclerosis (MS), and to provide evidence for its early diagnosis, prognostic evaluation and clinical intervention. First Hospital of Shanxi Medical University, Taiyuan, China.Huiru Xue †, Zhenzhen Yang †, Li Wang, Yayun Jiang, Jiayang Li, Minghui Wu, Guilian Wang, Yuanyuan Zhang * and Meini Zhang *

Ms symptoms checklist disability